Publications:
24. X. Gao, N. Arenas-Ramirez, S.J. Scales & R.N. Hannoush*. Membrane targeting of palmitoylated Wnt and Hedgehog revealed by chemical probes. FEBS Letters 2011, in press, PDF
23. R.N. Hannoush. Profiling myristoylated and palmityolated proteins using w-alkynyl fatty acids. In Chemical genomics and proteomics, Methods Mol. Biol. 2011, in press, PDF
22. R.N. Hannoush. Development of chemical probes for biochemical detection and cellular imaging of myristoylated and palmitoylated proteins. Curr. Protoc. Chemical Biology 2011, 3, 15-26. PDF
21. Y. Gong, E. Bourhis, C. Chiu, S. Stawicki, V.I. DeAlmeida, B.Y. Liu, K. Phamluong, T.C. Cao, R. Carano, J.A. Ernst, M. Solloway, B. Rubinfeld, R.N. Hannoush, Y. Wu, P. Polakis & M. Costa*. Wnt Isoform-specific Interactions with Co-receptor Specify Inhibition or Potentiation of Signaling by LRP6 Antibodies PLoS One 2010, 5(9): e12682 PDF.
20. R.N. Hannoush* and JingLucy Sun. The chemical toolbox for monitoring protein fatty acylation and prenylation. Nature Chemical Biology 2010, 6, 498 - 506. PDF
19. E. Bourhis, C. Tam, Y. Frank, J. Bazan, J. Ernst, J. Huang, M. Costa, A. Cochran & R.N. Hannoush*. Reconstitution of a Frizzled8-Wnt3a-LR6 complex reveals multiple Wnt and Dkk1 binding sites on LRP6. J. Biol. Chem. 2010, 285, 9172-9. abstract, PDF
18. N. Burns, I. Krylova, R.N. Hannoush & P.S. Baran*. Scalable Total Synthesis and Biological Evaluation of Haouamine A and Its Atropisomer. J. Am. Chem. Soc. 2009, 131, 9172-3. PDF
17. R.N. Hannoush* & N. Arenas-Ramirez. Imaging the lipidome: w-alkynyl fatty acids for detection and cellular visualization of lipid-modified proteins. ACS Chem. Biol. 2009, 4, 581-587. PDF
Highlighted in J. Proteome Res. 2009. link
Featured on journal coverpage. link
16. Y. Zhang, B.A. Appleton, C. Wiesmann, T. Lau, M. Costa, R.N. Hannoush* & S.S. Sidhu*. Inhibition of Wnt signaling by Dishevelled PDZ peptides. Nature Chemical Biology 2009, 5, 217-9 (PDF)
Highlighted in C&E News 2009, 87, 29.
15. R.N. Hannoush. Kinetics of Wnt-Driven β-Catenin Stabilization Revealed by Quantitative and Temporal Imaging. PLoS One 2008, 3(10), e3498. PDF
14. R.N. Hannoush. Probing Cellular Systems with Chemistry. Nature Chemical Biology 2007, 3, 131-134. PDF
graduate and postdoctoral:
13. R.N. Hannoush, B.C. Goess, M.D. Shair, T. Kirchhausen. Reversible Small Molecule-Induced Separation of Mammalian Golgi Cisternae. (2010) in preparation
12. B. C. Goess, R. N. Hannoush, L. K. Chan, T. Kirchhausen, M. D. Shair. Synthesis of a 10,000-membered Library of Molecules Resembling Carpanone and Discovery of Vesicular Traffic Inhibitors. J. Am. Chem. Soc. (2006), 128, 5391-5403. PDF
11. R.N. Hannoush, M.J. Damha. Preference for Ribose over Deoxyribose in Loop-Closing Base Pairs of Extra Stable Nucleic Acid Hairpins. Nucleosides & Nucleotides (2005), 24, 1519-1530. PDF
10. C. G. Peng, R. N. Hannoush, M. J. Damha. Synthesis of a “taller” 2',5'-Linked Ribonucleic Acid: 2'-α-C-hydroxymethyl 2',5'-linked RNA. J. Biomol. Struct. Dyn. 2005, 22, 856-857.
9. R.N. Hannoush, K.-L Min, M.J. Damha. Diversity-Oriented Solid-Phase Synthesis and Biological Evaluation of Oligonucleotide Hairpins as HIV-1 RT RNase H Inhibitors. Nucleic Acids Res. (2004), 32. 6164-6175. (Featured on the cover page) PDF
8. B. Lamontagne, R.N. Hannoush, M.J. Damha, S.A. Elela. Molecular Requirements for Duplex Recognition and Cleavage by RNase III: Discovery of an RNA-dependent DNA Cleavage Activity by Yeast Rnt1p. J. Mol. Biol. (2004), 338, 401-418. PDF
7. R.N. Hannoush, S. Carriero, K.-L. Min, M.J. Damha. Selective Inhibition of HIV-1 Reverse Transcriptase (HIV-1 RT) RNase H by Small RNA Hairpins and Dumbbells. ChemBioChem. (2004), 5, 527-533. PDF
6. R.N. Hannoush, A. Y. Denisov, K. Gehring, M.J. Damha. Structure of 2',5'-Linked Tetraribonucleotide Loops: A Novel RNA Motif. Nucleosides & Nucleotides (2003), 22, 1687-1690. PDF
5. R.N. Hannoush, A-Y. Denisov, K. Gehring, M.J. Damha. A New RNA Fold: RNA Hairpins Containing Unusually Stable 2',5'-Linked r(UUCG) Loops. J. Biomol. Struct. Dyn. (2003), 20 (6), 836-837.
4. A.-Y. Denisov, R.N. Hannoush, K. Gehring, M.J. Damha. A Novel RNA Motif Based on the Structure of Unusually Stable 2',5'-r(UUCG) Loops. J. Am. Chem. Soc. (2003), 125, 11525-11531. PDF
3. R.N. Hannoush, M.J. Damha. Remarkable Stability of Hairpins Containing 2',5'-Linked RNA Loops. J. Am. Chem. Soc. (2001), 123, 12368 –12374. PDF
2. R.N. Hannoush, M.J. Damha. Extra Stable 2',5'-Linked RNA Loops. Nucleosides & Nucleotides (2001), 20, 1201-1204.
1. R.N. Hannoush, M.J. Damha. Structure and Thermodynamics of Hairpins containing 2',5'-Linked RNA Loops. J. Biomol. Struct. Dyn. (2001), 18 (6), 906.
Patents:
M.J. Damha, R. N. Hannoush, K.-L. Min, S. Carriero. Compositions and methods for the preparation of oligodeoxyribonucleotides and inhibiting RNase H activity of retroid reverse transcriptase. U.S. Pat. Appl. Publ. 2004 / US 2004138166.
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