Publications:
19. E. Bourhis, C. Tam, Y. Frank, J. Bazan, J. Ernst, J. Huang, M. Costa, A. Cochran & R.N. Hannoush*. Reconstitution of a Frizzled8-Wnt3a-LR6 complex reveals multiple Wnt and Dkk1 binding sites on LRP6. J. Biol. Chem. 2010, in press. abstract, PDF
18. N. Burns, I. Krylova, R.N. Hannoush & P.S. Baran*. Scalable Total Synthesis and Biological Evaluation of Haouamine A and Its Atropisomer. J. Am. Chem. Soc. 2009, 131, 9172-3. PDF
17. R.N. Hannoush* & N. Arenas-Ramirez. Imaging the lipidome: w-alkynyl fatty acids for detection and cellular visualization of lipid-modified proteins. ACS Chem. Biol. 2009, 4, 581-587. PDF
Highlighted in J. Proteome Res. 2009. link
Featured on journal coverpage. link
16. Y. Zhang, B.A. Appleton, C. Wiesmann, T. Lau, M. Costa, R.N. Hannoush* & S.S. Sidhu*. Inhibition of Wnt signaling by Dishevelled PDZ peptides. Nat. Chem. Biol. 2009, 5, 217-9 (PDF)
Highlighted in C&E News 2009, 87, 29.
15. R.N. Hannoush. Kinetics of Wnt-Driven β-Catenin Stabilization Revealed by Quantitative and Temporal Imaging. PLoS One 2008, 3(10), e3498. PDF
14. R.N. Hannoush. Probing Cellular Systems with Chemistry. Nat. Chem. Biol. 2007, 3, 131-134. PDF
graduate and postdoctoral:
13. R.N. Hannoush, B.C. Goess, M.D. Shair, T. Kirchhausen. Reversible Small Molecule-Induced Separation of Mammalian Golgi Cisternae. (2009) Submitted
12. B. C. Goess, R. N. Hannoush, L. K. Chan, T. Kirchhausen, M. D. Shair. Synthesis of a 10,000-membered Library of Molecules Resembling Carpanone and Discovery of Vesicular Traffic Inhibitors. J. Am. Chem. Soc. (2006), 128, 5391-5403. PDF
11. R.N. Hannoush, M.J. Damha. Preference for Ribose over Deoxyribose in Loop-Closing Base Pairs of Extra Stable Nucleic Acid Hairpins. Nucleosides & Nucleotides (2005), 24, 1519-1530. PDF
10. C. G. Peng, R. N. Hannoush, M. J. Damha. Synthesis of a “taller” 2',5'-Linked Ribonucleic Acid: 2'-α-C-hydroxymethyl 2',5'-linked RNA. J. Biomol. Struct. Dyn. 2005, 22, 856-857.
9. R.N. Hannoush, K.-L Min, M.J. Damha. Diversity-Oriented Solid-Phase Synthesis and Biological Evaluation of Oligonucleotide Hairpins as HIV-1 RT RNase H Inhibitors. Nucleic Acids Res. (2004), 32. 6164-6175. (Featured on the cover page) PDF
8. B. Lamontagne, R.N. Hannoush, M.J. Damha, S.A. Elela. Molecular Requirements for Duplex Recognition and Cleavage by RNase III: Discovery of an RNA-dependent DNA Cleavage Activity by Yeast Rnt1p. J. Mol. Biol. (2004), 338, 401-418. PDF
7. R.N. Hannoush, S. Carriero, K.-L. Min, M.J. Damha. Selective Inhibition of HIV-1 Reverse Transcriptase (HIV-1 RT) RNase H by Small RNA Hairpins and Dumbbells. ChemBioChem. (2004), 5, 527-533. PDF
6. R.N. Hannoush, A. Y. Denisov, K. Gehring, M.J. Damha. Structure of 2',5'-Linked Tetraribonucleotide Loops: A Novel RNA Motif. Nucleosides & Nucleotides (2003), 22, 1687-1690. PDF
5. R.N. Hannoush, A-Y. Denisov, K. Gehring, M.J. Damha. A New RNA Fold: RNA Hairpins Containing Unusually Stable 2',5'-Linked r(UUCG) Loops. J. Biomol. Struct. Dyn. (2003), 20 (6), 836-837.
4. A.-Y. Denisov, R.N. Hannoush, K. Gehring, M.J. Damha. A Novel RNA Motif Based on the Structure of Unusually Stable 2',5'-r(UUCG) Loops. J. Am. Chem. Soc. (2003), 125, 11525-11531. PDF
3. R.N. Hannoush, M.J. Damha. Remarkable Stability of Hairpins Containing 2',5'-Linked RNA Loops. J. Am. Chem. Soc. (2001), 123, 12368 –12374. PDF
2. R.N. Hannoush, M.J. Damha. Extra Stable 2',5'-Linked RNA Loops. Nucleosides & Nucleotides (2001), 20, 1201-1204.
1. R.N. Hannoush, M.J. Damha. Structure and Thermodynamics of Hairpins containing 2',5'-Linked RNA Loops. J. Biomol. Struct. Dyn. (2001), 18 (6), 906.
Patents:
M.J. Damha, R. N. Hannoush, K.-L. Min, S. Carriero. Compositions and methods for the preparation of oligodeoxyribonucleotides and inhibiting RNase H activity of retroid reverse transcriptase. U.S. Pat. Appl. Publ. 2004 / US 2004138166.
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